Rheumatology Medication Guides | Prime Rheumatology Clinic

Medication Guides

The medication guides provide streamlined information on the administration of biologic, antiresorptive, and other medications used to treat patients with rheumatic disease.

The guides are intended to assist rheumatologists, advanced practice providers (NP and PA), health professionals new to rheumatology, or people who need basic information about the agents.

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What Are Common Treatments?

A disease-modifying anti-rheumatic drug (DMARD) is usually the first treatment usually prescribed for RA. Common DMARDs include methotrexate, leflunomide, hydroxychloroquine, and sulfasalazine. If DMARDs alone don’t control RA inflammation, a rheumatologist may prescribe a biologic drug such as abatacept, adalimumab, etanercept, tocilizumab, or medications such as tofacitinib or upadacitinib. No single treatment works for all patients, and many people may change their treatment at least once during their lifetime. A rheumatologist will help find a treatment plan that is best for you.

Living with RA

Regular follow up with your rheumatologist is key to proper disease control and reduced risk of joint damage. Take all medications as prescribed, and notify your doctor if drugs cause any side effects or problems. Follow an anti-inflammatory diet and engage in low-impact aerobic exercises, such as walking, or swimming to boost muscle strength. Smoking cessation is also highly important if you’re a smoker since there is a known association of tobacco use and rheumatoid arthritis. Certain supplements such as omega-3, vitamin D or turmeric have also been shown to improve pain in patients with RA but always check with your doctor if they are appropriate for you. Supplements do not replace the treatment with medications for RA.

Updated February 2025 by Diana Girnita, MD, PhD, and reviewed by the American College of Rheumatology Committee on Communications and Marketing.

This information is provided for general education only. Individuals should consult a qualified health care provider for professional medical advice, diagnosis and treatment of a medical or health condition.